transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers. /working-with-us. At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In
oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change.
We bring a human touch to every treatment we pioneer. Join us and make a difference. Position Summary The Principal Scientist, CV Pharmacology will the lead pharmacology initiatives supporting our pipeline in Cardiovascular Drug Discovery. The position requires subject matter expertise in heart disease and the ability to work independently and collaboratively in a team-driven environment. The role involves people management and potential hands-on work in the laboratory,
as needed. The ability to provide input on the in vivo strategy of CV programs is vital to this role.
This position is based in Brisbane, CA. Key Responsibilities Supervise talented scientist staff with expertise in CV pharmacology, predominantly focused on cardiac in vivo physiology. Laboratory leadership via hands-on experimentation and troubleshooting; expert in cardiac mechanics using invasive hemodynamics and echocardiography; experience handling animals for disease heart research. Ensure smooth interactions and appropriate support levels to facilitate drug discovery progression within the working groups. Ensure appropriate interface with translational research and early development teams to ensure pre-clinical pharmacological testing supports molecule progression into the clinic.
Establish and implement a strategy to identify and validate new pharmacological models. Be a contributor to the overall drug discovery strategy development within CV Drug Discovery; past drug target leadership is a plus. Support compliance with institutional animal care and use policies. Day to day responsibilities include team management in the laboratory, data and protocol reviews, presentations to working groups and upper management, training staff in sophisticated CV experimental methods as needed, hands-on laboratory experimentation.
Manage the career progression of CV Pharmacology team, as needed. Write pharmacology reports and regulatory documents to support FDA filings. Contribute to the leadership of the CV Drug Discovery team; policy matters, recruitment initiatives, succession planning, diversity. backss pharmacological suitability of potential business development opportunities, as needed. Basic Qualifications Bachelor's Degree 8+ years of academic and / or industry experience Or Master's Degree 6+ years of academic and / or industry experience Or Ph.
D. or equivalent advanced degree in the Life Sciences 4+ years of academic and / or industry experience Preferred Qualifications & Experience Ph. D. or equivalent advanced degree in the Life Sciences Ph D; 4+ years of academic and / or industry experience. Hands-on role as needed; expertise in cardiac mechanics (hemodynamics and imaging modalities) Expertise in the field of CV Pharmacology with a strong focus on heart failure; understanding of sarcomere biology, physiology and related drug targets is a plus. Prior drug discovery expertise within an industrial setting is highly desirable.
Strong core belief in the care of animals; understanding of animal welfare ethics and policy. Understanding of KO and transgenic model creation. Demonstrated success in interfacing with development teams and team leaders. Demonstrated success in line-managing teams of scientists via direct reporting or dotted line management. Excellent verbal and written communication skills. Commitment to developing one's own leadership skills via participation in scientific management training. The starting compensation for this job is a range from $121,000 - $152,000 plus incentive cash and stock opportunities (based on eligibility).
The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience. For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location. Why You Should Apply Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as " Transforming patients' lives through science™ " every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to xyz X@.
Visit careers. /eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
degrader compounds and drive drug discovery efforts for both platform and pipeline projects. You should be able to work independently while contributing to a team environment and manage several projects simultaneously. The successful candidate must stay current with applicable internal/external scientific literature and be able to analyze, document, and report data rigorously.
You should possess excellent communication skills and be proficient in presenting in front of groups. Join our team at Abbvie and contribute to ground-breaking research in the field of target protein degradation. Responsibilities: Independently conceive and execute rigorous scientific research to profile potency,
efficacy, and mechanism of action for degraders (including, but not limited to ternary complex formation and ubiquitination) utilizing plate-based biochemical/cellular assays and quantitative western blot Innovate by developing novel biochemical and cellular assays to support structure-activity relationship (SAR) studies for degraders Drive and contribute to pipeline projects in collaboration with Therapeutic Area and Platform biology leads.
Demonstrate a high level of initiative and proficiency in troubleshooting experiments and be an internal leader by example for high standards in data analysis and quality Maintain good written records of laboratory procedures and communicate research
findings in cross-functional project team meetings and publications.
Qualifications: Position will be filled at level commensurate with extent of education, experience, and accomplishments Scientist II: BS in Biochemistry, Biophysics, Molecular Biology, Cell Biology, or related field of Biological Sciences with typically 7+ years of experience or MS and typically 5+ years of experience Sr Scientist I: BS Biochemistry, Biophysics, Molecular Biology, Cell Biology, or related field of Biological Sciences with typically 10+ years of experience, MS and typically 8+ years of experience, or Ph D and typically 0+ years of experience Demonstrated track record of scientific achievement (publication/presentation record) Proven ability to develop, analyze, and interpret assays for interrogation of biological questions Proficiency in standard biochemical and/or cellular/molecular techniques such as TR-FRET, Alpha LISA, Western Blots, ELISA, and Nano BRET Expertise/background in ubiquitin proteasome system biology or targeted protein degradation preferred, but not required Experience in small molecule drug discovery in academia or industry preferred, but not required Excellent problem-solving and multi-tasking skills in a fast-paced environment Must be a team-player with strong oral and written communication skills Abb Vie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion.
It is Abb Vie's policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, interaction (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, interactionual orientation, marital status, status as a protected veteran, or any other legally protected group status.
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