Sr. Scientist - Bioassay Screening - Biotherapeutic Drug Discovery | Alabaster, AL

communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. Lilly's Biotechnology Discovery Research Organization in San Diego is dedicated to discovery and development of biotherapeutics spanning a wide range of therapeutic areas.

Our commitment to innovation drives continuous improvement in patient outcomes through drug discovery, engineering, and characterization while leveraging cutting-edge automation to bolster many of these workflows. At the helm are an accomplished team of scientists and engineers that spearhead initiatives that bring

us closer to the next life-saving breakthrough. It's an exciting time to join Team Lilly! Responsibilities: As a member of the Lilly Biologics Screening Group and Automation Team, the focus of the successful candidate will be to support research teams across multiple therapeutic areas by miniaturizing, adapting and executing assays to screen biologics using state-of-the-art lab automation.

The successful candidate will thrive in a fast-paced, highly collaborative environment in which they work synergistically and creatively with local colleagues and multiple project teams across the organization. Key Objectives/Deliverables: The candidate will interface with multiple project teams across

the organization and outside Lilly to adapt bioassays to mid-high throughput automated formats (96W/384W), validate and execute screens, and identify hits for biologics discovery efforts using state-of-the-art automation platforms.

They will also develop de novo cell-based assays as needed. The candid will apply specialized commercial and internal software tools to perform detailed analysis of biological activity, statistical evaluation of assay performance and generate comprehensive data reports. The successful candidate will work with automation engineers to create, troubleshoot, and validate automated methods on liquid handling systems and workstations. The successful candidate will engage in the identification and evaluation of novel procedures or technologies that could serve to bolster the productivity of the antibody discovery and protein engineering teams or help in development of new capabilities for the screening group The candidate will clearly present results to collaborators, participate in project team meetings and present at internal forums The candidate will maintain clear, organized data, SOPs, and electronic notebook entries with great attention to detail Basic Qualifications: B.

S or M. S. in biology, biotechnology, biochemistry, molecular biology, or a related field with 3+ years relevant research experience in assay development & execution, preferably in drug discovery Additional Skills and Preferences: Proficient in assay development, optimization and troubleshooting of plate-based bioassays in 96/384W formats.

Demonstrated expertise in diverse assay methods and technologies, such as reporter bioassays, ELISA, FRET/BRET, Alpha-ELISA and co-culture assays Solid skills in cell culture techniques required with working knowledge of cellular signaling Experience working on an automated platform in a screening group is preferred.

Demonstrated ability to use multiple software platforms for plotting and statistical analysis of large experimental data sets (e. g. TIBCO Spotfire, Graphpad Prism, Genedata Screener) is preferred. Demonstrated ability to successfully take on challenges and quickly adapt to new responsibilities. Detail-oriented and highly organized with the ability to run and prioritize multiple projects to meet timelines Excellent written and oral communication skills, with a demonstrated ability to work in a highly collaborative team environment. Highly motivated with ability to work and think independently, research the literature, and master new skills, methods and technologies that enhance departmental capabilities highly preferred.

Additional Information: Location: San Diego, California Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively " Lilly" ) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( xyz X@lists. ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process.

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