Associate Scientist, Bioprocess Technologies and Engineering - BPD | Gaithersburg, MD

Astra Zeneca in Gaithersburg, MD: Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US.

Here, we play host to some of the most innovative technology and lab spaces, all designed to inspire collaboration and multi-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration. The Gaithersburg site offers a variety of amenities to help boost productivity and help

keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center.

This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams. Summary of the group: The Bioprocess Technologies and Engineering team is working to develop and apply new technologies to manufacture life-changing biologics in multiple therapeutic areas. As a cell culture scientist in Bioprocess Technologies and Engineering (BTE), you will join a team developing Astra Zeneca's Next Generation Manufacturing platform,

where we use engineering and science to understand and tackle problems.

Our team works with bioreactors and genetically modified Chinese hamster ovary cells to produce new drugs, and are developing new methods to improve productivity and product quality, so that we can provide our medicines to patients around the world. Main Duties & Responsibilities: This position within the Bioprocess Technologies and Engineering team involves working multi-functionally with the Cell Line Development and Engineering team, to develop new procedures and methods to improve the engineering and identification of production cell lines suitable for the Next Generation Manufacturing process.

You will be developing strategies and transferring knowledge to other development scientists. Additionally, you will be leading and advising scientists in adjacent groups on best practices. Application of perfusion and continuous processes to gene and cell therapies are also possible. Major responsibilities include: Developing next generation mammalian clone screening processes, including cell culture consistency and performance, conduct cell culture experiments from transfection and expansion to the characterization of stable cell lines with high efficiency assays Supporting the Platform Continuous Cell Culture and Purification teams as well as the Platform Cell Line Development teams Writing work guides and SOPs to instruct other scientists on the best practice methods Collaborating with colleagues to augment existing in-process analytical systems and data historians Building or applying mathematical models that predict cell biology Developing automation methods that control the cell culture process Demonstrating leadership in science and technology Demonstrating ability to train peers in novel bioprocessing methods Presenting at internal departmental and multi-functional meetings, and may participate/present at external meetings Ensure that work is performed in accordance with Safety, Health and Environment regulations and Astra Zeneca best practices Education & Experience Requirements: Degree in STEM related fields including biochemical engineering, biochemistry, cell biology, genetics, molecular biology, and biological sciences Bachelor's degree or MS with 0+ years of related experience in industry or academia Required Skills: Aseptic technique Basic molecular biology and cloning techniques, including vector construction and PCR Experience with data and statistical analysis Problem solving and scientific reasoning Ability to work independently Ability to lead development projects Strong communication skills with peers and management Effective planning and organization skills High level of attention to detail and ability to independently solve scientific and technical problems Desired Skills: Suspension cell culture experience Analytical techniques such as titer and product quality analysis and flow cytometry Experience with robotics and high-throughput processes Programming in Python, Mat Lab, R, or other scientific language Fundamental understanding of field of scientific study Why Astra Zeneca?

We are proud to work for Astra Zeneca for many reasons. Most recently, we are proud of our development of a vaccine and antibodies to treat or prevent COVID19. During the pandemic, we have pledged to forgo any profit from these products! And we are making these products available globally! We are working incredibly hard on these and other projects, and need you to join us so we can be successful. Astra Zeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big.

Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-medical company can be. This means we're opening new ways to work, pioneering groundbreaking methods and bringing unexpected teams together. Interested? Come and join our journey. So, what's next! Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it's yours. Where can I find out more? Check out our landing page for more information on our BPD group careers.

/bpd Our Social Media, Follow Astra Zeneca on Linked In /company/1603/ Follow Astra Zeneca on Facebook /astrazenecacareers/ Follow Astra Zeneca on Instagram /astrazeneca_careers/? hl=en Date Posted 21-Nov-2023 Closing Date Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be.

We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e. g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.